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Moderated Online Social Therapy (MOST) in early intervention for psychosis services: a pilot randomised controlled study

درمان اجتماعی آنلاین با نظارت (MOST) در خدمات مداخله زودهنگام برای روان‌پریشی: یک مطالعه آزمایشی تصادفی‌شده کنترل‌شده

Sophie Mae Harrington, Maeve Dwan-O'Reilly, Scott Mahon, Conor Gavin, Megan Cowman, Anna O’Mahony Sinnott, Emily Barrett, Emma Frawley, Tom Burke, Brian P. Hallahan, Colm McDonald, K. O’Connor, Max Birchwood, Caroline Heary, Mario Álvarez‐Jiménez, Gary J Donohoe

Irish Journal of Psychological Medicine 2026, pp. 1-11
https://doi.org/10.1017/ipm.2026.10222

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چکیده

INTRODUCTION: Psychosis is a significant cause of reduced social and occupational function in those aged 18-35 years. This study investigates the feasibility of enhancing currently available Early Intervention for Psychosis (EIP) care using a moderated online intervention comprising therapist-supported online therapeutic interventions and peer-to-peer social mentoring and networking. METHODS: The trial explores data relevant to establishing the feasibility of delivering MOST to patients enrolled in EIP services and estimation of effect sizes for pre-post measures administered to inform power calculations for a full trial. RESULTS: A total of 35 patients with early psychosis were recruited during the study period, with 17 (48.6%) retained in the study at 6 months. In the intervention arm, 65.4% of participants engaged with MOST for 5 weeks or more but only 15.4% continued to engage at six months. At six months, calculation of effect sizes for pre-post changes indicated small to moderate improvements in social and occupational function, small changes in clinical symptom severity and no changes in cognitive performance. DISCUSSION: Findings partially supported the feasibility of conducting a trial of MOST in Irish EIP services. Recruitment and study procedures were successfully completed, while retention and sustained engagement suggested that intervention duration, delivery, and positioning within the care pathway may require consideration for further study of this promising intervention in the Irish context.

چکیده به فارسی

مقدمه: روان‌پریشی یکی از علل مهم کاهش عملکرد اجتماعی و شغلی در افراد ۱۸ تا ۳۵ سال است. این مطالعه امکان‌سنجی ارتقای مراقبت‌های موجود مداخله زودهنگام برای روان‌پریشی (EIP) را با استفاده از یک مداخله آنلاین با نظارت، شامل مداخلات درمانی آنلاین با حمایت درمانگر و راهنمایی و شبکه‌سازی اجتماعی همتایان، مورد بررسی قرار می‌دهد. روش‌ها: این کارآزمایی داده‌های مرتبط با امکان‌سنجی ارائه MOST به بیماران ثبت‌نام‌شده در خدمات EIP و برآورد اندازه اثر برای سنجش‌های پیش و پس از مداخله را به منظور اطلاع‌رسانی محاسبات توان برای یک کارآزمایی کامل بررسی می‌کند. نتایج: در مجموع ۳۵ بیمار با روان‌پریشی زودهنگام در دوره مطالعه جذب شدند که ۱۷ نفر (۴۸/۶٪) در شش ماه در مطالعه باقی ماندند. در گروه مداخله، ۶۵/۴٪ از شرکت‌کنندگان به مدت ۵ هفته یا بیشتر با MOST درگیر بودند، اما تنها ۱۵/۴٪ در شش ماهگی همچنان مشارکت داشتند. در شش ماهگی، محاسبه اندازه اثر برای تغییرات پیش و پس از مداخله نشان‌دهنده بهبودهای کوچک تا متوسط در عملکرد اجتماعی و شغلی، تغییرات اندک در شدت علائم بالینی و عدم تغییر در عملکرد شناختی بود. بحث: یافته‌ها تا حدی امکان‌سنجی انجام کارآزمایی MOST در خدمات EIP ایرلند را تأیید کردند. جذب و رویه‌های مطالعه با موفقیت انجام شد، در حالی که حفظ و تداوم مشارکت نشان داد که مدت، نحوه ارائه و جایگاه مداخله در مسیر مراقبت ممکن است برای مطالعه بیشتر این مداخله امیدبخش در زمینه ایرلند نیازمند بررسی باشد.

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موضوع‌ها و کلیدواژه‌ها

امیددرمانشناختclinical trialsEarly psychosisIntervention (counseling)IrishPsychological interventionpsychosisکارآزمایی تصادفی‌شده‌ی کنترل‌شدهSocial function

ارجاع

Harrington, S. M., Dwan-O'Reilly, M., Mahon, S., Gavin, C., Cowman, M., Sinnott, A. O., Barrett, E., Frawley, E., Burke, T., Hallahan, B. P., McDonald, C., O’Connor, K., Birchwood, M., Heary, C., Álvarez‐Jiménez, M., & Donohoe, G. J. (2026). Moderated Online Social Therapy (MOST) in early intervention for psychosis services: a pilot randomised controlled study. Irish Journal of Psychological Medicine, 1–11. https://doi.org/10.1017/ipm.2026.10222

(Harrington et al., 2026)

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قوانین پرسش و گفتگو
  1. با احترام و بدون توهین، تحقیر، برچسب‌زنی یا حمله‌ی شخصی با دیگران گفتگو کنید.
  2. از نوشتن هرگونه اطلاعات هویتی یا قابل‌شناسایی مراجعان، بیماران یا اشخاص ثالث، از جمله نام، شماره‌ی تماس، تصویر، نشانی، محل کار یا جزئیات منحصربه‌فرد پرونده خودداری کنید.
  3. اگر درباره‌ی یک تجربه‌ی بالینی سؤال می‌کنید، اطلاعات را تا حد ممکن بی‌نام و کلی بیان کنید تا امکان شناسایی فرد وجود نداشته باشد.
  4. این بخش برای یادگیری و گفت‌وگوی علمی است و جایگزین ارزیابی، تشخیص، مشاوره یا روان‌درمانی شخصی نیست.
  5. در شرایط بحران یا خطر آسیب به خود یا دیگران، به این بخش اتکا نکنید و برای دریافت کمک فوری با اورژانس اجتماعی ۱۲۳ یا صدای مشاور بهزیستی ۱۴۸۰ تماس بگیرید.
  6. انتشار تبلیغات، معرفی خدمات شخصی، شماره‌ی تلفن، شناسه‌ی شبکه‌های اجتماعی، پیوند تبلیغاتی یا درخواست جذب مراجع در این بخش مجاز نیست.
  7. در بیان ادعاهای علمی، به‌ویژه درباره‌ی اثربخشی درمان‌ها، تشخیص یا یافته‌های پژوهشی، تا حد امکان نام منبع معتبر، مقاله یا راهنمای علمی را ذکر کنید.
  8. از ارائه‌ی تشخیص قطعی، تجویز درمان یا دارو و توصیه‌های بالینی شخصی به سایر کاربران خودداری کنید.
  9. پاسخ‌هایی که کارشناسان فکر بنیان می‌دهند با برچسب «پاسخ فکر بنیان» یا «کارشناس فکر بنیان» نمایش داده می‌شوند و سایر نوشته‌ها بیانگر نظر کاربران هستند.
  10. گزارش نوشته‌ی نامناسب: اگر نوشته‌ای حاوی نقض محرمانگی، محتوای آسیب‌زا، توهین، تبلیغ یا تخلف از این قوانین است، گزینه‌ی «گزارش» را انتخاب کنید تا تیم سایت بررسی کند.

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چکیده

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