perinatal factors

Background The first period of life shapes later life chances, but the economic consequences accumulate across later childhood, adolescence and adulthood and fall across several policy sectors. Existing reviews typically address one risk factor at a time, or focus on a restricted outcome domain, leaving the relevant evidence scattered. This umbrella review collates review-level evidence on how early childhood exposures affect later economic outcomes. Methods The review was registered on Open Science Framework (https://osf.io/szpx5/overview). Medline, APA PsycArticles, APA PsycINFO, CINAHL Plus with Full Text, Education Research Complete & Psychology and Behavioural Sciences Collection databases were searched in November 2025. Systematic, rapid, scoping, narrative and umbrella reviews were eligible if they examined early childhood exposures and later outcomes with measurable consequences for education, employment, income, criminal justice involvement, quality of life, wellbeing or service costs. Reviews reporting only health status outcomes, and those focused on low- and middle-income countries, were excluded. Two authors screened and extracted independently, and quality was appraised. Findings were synthesised narratively. Results Seventy-two reviews were included, published between 2001 and 2025 and increasingly since 2021. Adverse childhood experiences and related adversity were the most frequently examined exposures, followed by childhood physical health conditions, birth and perinatal factors, and neurodevelopmental and behavioural difficulties. Early years risk factors were consistently associated with poorer later education and employment, lower income and greater criminal justice involvement. Evidence on quality of life was mixed, and service use and costs were seldom reported. Few reviews addressed publication bias. Conclusion Difficulties experienced in the early years have consequences across several later life domains and public sectors. The evidence is most consistent for education and criminal justice involvement, and thinner for quality of life, service use and costs. Reviews rarely address correlations between risk factors or the pathways connecting them to later outcomes. Modelling these pathways and evaluating interventions to address early years risks are priorities. Limitations of the review were the inclusion of studies that covered a wide range of age groups and the exclusion of health outcomes.

Problems associated with mental development during the first years of life remain among the most significant medical and social challenges, since this period is characterized by particularly high neuroplasticity, while timely iden­tification of possible developmental deviations is of crucial importance. The study is aimed at systematizing modern strategies for the early prevention of mental developmental disorders, taking into account clinical, psychological, and social aspects. The major biological, perinatal, family, and social factors that may influence the development of the child’s cognitive, emotional, speech, and behavioral domains are analyzed. Particular emphasis is placed on the early iden­tification of developmental delays, assessment of emotional interaction between parents and the child, as well as detection of unfavorable conditions in the family environment, chronic stress, attachment deficits, and insufficient developmental stimulation. The need for interdisciplinary cooperation among pediatricians, child neurologists, psychiatrists, psycholo­gists, primary healthcare professionals, and social service specialists is emphasized. Contemporary effective preventive measures should focus not only on disorders that have already become clinically apparent, but also on the active identification of high-risk groups, regular monitoring of the child’s devel­opmental status, and the earliest possible initiation of corrective and developmental intervention programs. Such a comprehensive approach can improve the effectiveness of early support, reduce the severity of subsequent cognitive and emotional-behavioral problems, and contribute to better social adaptation of the child and overall well-being of the family.

مسائل مرتبط با رشد روانی در سال‌های نخست زندگی همچنان از مهم‌ترین چالش‌های پزشکی و اجتماعی به‌شمار می‌روند، زیرا این دوره با نوروپلاستیسیتی بسیار بالا مشخص می‌شود و شناسایی به‌موقع انحرافات احتمالی رشد از اهمیت حیاتی برخوردار است. هدف این مطالعه، نظام‌مند ساختن راهبردهای نوین برای پیشگیری زودهنگام از اختلالات رشد روانی با در نظر گرفتن جنبه‌های بالینی، روان‌شناختی و اجتماعی است. عوامل زیستی، پیرامون تولد، خانوادگی و اجتماعی عمده که ممکن است بر رشد حوزه‌های شناختی، هیجانی، گفتاری و رفتاری کودک تأثیرگذار باشند، مورد تحلیل قرار گرفته‌اند. تأکید ویژه‌ای بر شناسایی زودهنگام تأخیرهای رشدی، ارزیابی تعامل هیجانی والدین و کودک، همچنین شناسایی شرایط نامطلوب در محیط خانواده، استرس مزمن، کمبود دلبستگی و تحریک ناکافی رشد صورت گرفته است. ضرورت همکاری میان‌رشته‌ای میان متخصصان کودکان، نورولوژیست‌های کودکان، روان‌پزشکان، روان‌شناسان، کارکنان مراقبت‌های اولیه سلامت و متخصصان خدمات اجتماعی مورد تأکید قرار گرفته است. اقدامات پیشگیرانه مؤثر معاصر باید نه تنها بر اختلالاتی که به‌طور بالینی آشکار شده‌اند متمرکز باشند، بلکه شناسایی فعال گروه‌های پرخطر، پایش منظم وضعیت رشد کودک و آغاز هرچه زودتر برنامه‌های مداخله‌ای اصلاحی و رشدی را نیز دربرگیرند. چنین رویکرد جامعی می‌تواند اثربخشی حمایت زودهنگام را افزایش داده، شدت مشکلات شناختی و هیجانی-رفتاری بعدی را کاهش داده و به سازگاری اجتماعی بهتر کودک و بهزیستی کلی خانواده کمک کند.