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diabetes diagnosis

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Diagnosis is not enough: Selective behavior change after chronic disease onset in Thailand

Ruttiya Bhula‐or; Attakrit Leckcivilize PLoS ONE, 2026, Vol. 21, Issue 10, pp. e0360648 https://doi.org/10.1371/journal.pone.0360648

چکیده

Health shocks—such as new diagnoses of chronic disease—can disrupt daily life and create potential “teachable moments” for behavioral improvement. Yet, existing evidence on post-diagnosis behavior change remains mixed and largely limited to high-income countries. This study addresses a major empirical gap by examining whether chronic disease diagnoses are associated with measurable within-person changes in health behaviors among middle-aged and older adults in Thailand, a rapidly aging middle-income society. We analyzed four waves (2015–2022) of the Health, Aging, and Retirement in Thailand (HART) survey. The analytic sample comprised adults aged ≥45 years with no baseline diagnosis of cancer, diabetes, or cardiovascular disease (N = 2,891; 9,577 person-wave observations). Self-reported physician-diagnosed conditions were used to construct disease-status indicators. Behavioral outcomes included smoking, current alcohol use, sufficient physical activity (≥150 minutes/week), normal body mass index (BMI) (18.5–23), and waist obesity (sex-specific cutoffs). Individual fixed-effects linear probability models with survey-wave fixed effects and adjustment for time-varying covariates (log income, activities of daily living [ADL] score, and marital status) estimated within-person associations, with standard errors clustered at the individual level. Disease-specific models and models including interactions with sex assessed heterogeneity. In pooled analyses, the disease-status indicator was not significantly associated with smoking, alcohol use, physical activity, BMI, or waist obesity. In contrast, a diabetes diagnosis was associated with a reduction of 3.6 percentage-point in current alcohol use, and both diabetes and cancer diagnoses were associated with reductions in frequent drinking. Models including interactions with sex suggested larger diagnosis-associated reductions in selected alcohol-use outcomes among men, although statistical evidence varied by outcome and disease type. Among middle-aged and older Thai adults, chronic disease diagnoses were associated with selective, rather than comprehensive, changes in health behaviors. Diagnosis alone is insufficient to support changes across multiple health behaviors, underscoring the need for structured post-diagnosis counselling, follow-up, and gender-sensitive secondary prevention in aging middle-income populations.

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Prevalence of binge eating disorder symptoms and associated characteristics in Danish adults with type 2 diabetes: A cross‐sectional study

شیوع علائم اختلال پرخوری افراطی و ویژگی‌های مرتبط در بزرگسالان دانمارکی مبتلا به دیابت نوع ۲: یک مطالعه مقطعی

Pernille Fiil Nybo; Sidsel Louise Domazet; Michael Einar Røder; Jakob Linnet Diabetic Medicine, 2026, pp. e70489 https://doi.org/10.1111/dme.70489

چکیده

Abstract Aims Coexistence of binge eating disorder (BED) and type 2 diabetes is linked to poor health outcomes, but data on the prevalence and clinical profile of BED symptoms remain limited and inconsistent. We estimated the prevalence of BED symptoms and examined their associated clinical characteristics in Danish adults with type 2 diabetes. Methods We conducted a cross‐sectional study within the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort. Adults with type 2 diabetes completed the Binge Eating Disorder Questionnaire (BED‐Q) to determine the presence of BED symptoms. Data on well‐being, comorbidities, treatment and biomarkers were retrieved from national health registers. Associations between participant characteristics and BED symptoms were examined using Poisson regression to estimate prevalence ratios (PRs). Results Among 2459 individuals, 72 (2.9%) screened positive for BED symptoms, and 76 (3.1%) showed subclinical BED symptoms. Individuals with BED symptoms had an earlier age at diagnosis of type 2 diabetes (median 51.8 years, IQR: 41.3–57.6) than adults without BED symptoms (median 59.5 years, IQR: 52.1–66.2). BED symptoms were also associated with severe obesity (BMI ≥35 kg/m 2 ) (PR 11.37, 95% CI: 2.78–46.49), female sex (PR 1.54, 95% CI: 1.12–2.10), and lower well‐being (PR 1.83, 95% CI: 1.15–2.92). Conclusions BED symptoms were associated with a distinct clinical and psychosocial profile in Danish adults with type 2 diabetes. These findings support clinical awareness of BED symptoms in this population, particularly among women, individuals with obesity, those with lower well‐being and those diagnosed with diabetes at a younger age.

اهداف: هم‌زمانی اختلال پرخوری افراطی (BED) و دیابت نوع ۲ با پیامدهای نامطلوب سلامت مرتبط است، اما داده‌ها درباره شیوع و نمایه بالینی علائم BED محدود و ناسازگار باقی مانده‌اند. ما شیوع علائم BED را برآورد کردیم و ویژگی‌های بالینی مرتبط با آن‌ها را در بزرگسالان دانمارکی مبتلا به دیابت نوع ۲ بررسی نمودیم. روش‌ها: یک مطالعه مقطعی در چارچوب کوهورت مرکز دانمارکی پژوهش راهبردی در دیابت نوع ۲ (DD2) انجام شد. بزرگسالان مبتلا به دیابت نوع ۲ پرسشنامه اختلال پرخوری افراطی (BED-Q) را برای تعیین وجود علائم BED تکمیل کردند. داده‌های مربوط به سلامت روان، همبودی‌ها، درمان و نشانگرهای زیستی از سامانه‌های ملی ثبت سلامت استخراج شد. ارتباط بین ویژگی‌های شرکت‌کنندگان و علائم BED با استفاده از رگرسیون پواسون برای برآورد نسبت‌های شیوع (PRs) بررسی شد. نتایج: در میان ۲۴۵۹ نفر، ۷۲ نفر (۲٫۹٪) غربالگری مثبت برای علائم BED داشتند و ۷۶ نفر (۳٫۱٪) علائم زیر بالینی BED نشان دادند. افراد دارای علائم BED سن پایین‌تری در زمان تشخیص دیابت نوع ۲ داشتند (میانه ۵۱٫۸ سال، IQR: ۴۱٫۳–۵۷٫۶) نسبت به بزرگسالان بدون علائم BED (میانه ۵۹٫۵ سال، IQR: ۵۲٫۱–۶۶٫۲). علائم BED همچنین با چاقی شدید (BMI ≥35 kg/m2) (PR 11.37، 95% CI: 2.78–46.49)، جنسیت مؤنث (PR 1.54، 95% CI: 1.12–2.10) و سلامت روان پایین‌تر (PR 1.83، 95% CI: 1.15–2.92) مرتبط بود. نتیجه‌گیری: علائم BED با نمایه بالینی و روانی-اجتماعی متمایزی در بزرگسالان دانمارکی مبتلا به دیابت نوع ۲ همراه بود. این یافته‌ها بر اهمیت توجه بالینی به علائم BED در این جمعیت، به‌ویژه در میان زنان، افراد چاق، افراد با سلامت روان پایین‌تر و کسانی که در سنین پایین‌تر مبتلا به دیابت شده‌اند، تأکید می‌کند.

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