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Dose–response relationship between khat chewing frequency and sleep duration, perceived effects, and academic performance among medical students in Yemen

رابطه دوز-پاسخ بین فراوانی مصرف قات و مدت خواب، اثرات ادراک‌شده و عملکرد تحصیلی در میان دانشجویان پزشکی یمن

Abdalkhaliq Ahmad Obadi, Abdulelah H. Al‐Adhroey, Mohammed Abdullah Al Amad, Hamed Abdullah Salman, Ahmed Mohammed Alsaedi, Asad Ali Al-Yamani, Ebraheem Mohammed Mahyoob, Marwan Saeed Al-Pai, Alghazeer Ali Dughaish

Scientific Reports 2026
https://doi.org/10.1038/s41598-026-72988-9

متن کامل این مقاله در فکر بنیان نیست؛ مشخصات و چکیده را می‌بینید و متن کامل را می‌توانید از طریق DOI در سایت ناشر بخوانید. صفحه‌ی مقاله در سایت ناشر ↗

چکیده

Although khat chewing is common among university students in Yemen, evidence on dose–response relationships between khat chewing frequency and sleep duration, perceived effects, and academic performance remains limited. This study examined these associations among medical students at Thamar University, Yemen. A cross-sectional study was conducted among undergraduate medical students. Data were collected using a structured questionnaire. Khat chewing frequency was categorized as non-use, 1–2 days/week, 3–4 days/week, and 5–7 days/week. Multivariable logistic and linear regression analyses were performed to assess associations, and ordinal trend analyses were used to evaluate dose–response relationships. Adjusted odds ratios (AOR) and regression coefficients (β) with 95% confidence intervals (CI) were reported. Statistical significance was set at p < 0.05. Increasing khat chewing frequency was independently associated with higher odds of short sleep duration (< 6 h). Compared with non-chewers, the adjusted odds of short sleep increased progressively, reaching an AOR of 7.83 (95% CI: 3.70–16.57; P < 0.001) among daily chewers.A significant linear dose–response relationship was also observed (AOR = 1.97, 95% CI: 1.54–2.52; P < 0.001). Perceived-effects scores increased progressively with khat-chewing frequency, with adjusted mean differences of 3.36, 3.73, and 4.94 for 1–2, 3–4, and 5–7 days/week, respectively (all P ≤ 0.001), with a significant linear trend (adjusted β = 1.61, 95% CI: 1.29–1.92; P < 0.001). In contrast, academic performance showed no significant association or linear dose–response relationship with khat chewing (adjusted β = 0.22, 95% CI: −0.46–0.89; P = 0.532). Khat chewing frequency showed clear dose–response associations with short sleep duration and perceived effects among medical students. However, these associations did not translate into measurable differences in academic performance. These findings suggest that the effects of frequent khat use are more evident in sleep and perceived behavioural outcomes than in academic achievement. These findings are consistent with known stimulant-related effects and may extend to similar student populations in comparable settings.

چکیده به فارسی

اگرچه مصرف قات در میان دانشجویان دانشگاه‌های یمن رایج است، اما شواهد مربوط به روابط دوز-پاسخ بین فراوانی مصرف قات و مدت خواب، اثرات ادراک‌شده و عملکرد تحصیلی همچنان محدود است. این مطالعه این ارتباطات را در میان دانشجویان پزشکی دانشگاه ذمار، یمن بررسی کرد. یک مطالعه مقطعی در میان دانشجویان کارشناسی پزشکی انجام شد. داده‌ها با استفاده از پرسشنامه ساختاریافته جمع‌آوری شد. فراوانی مصرف قات به صورت عدم مصرف، ۱–۲ روز در هفته، ۳–۴ روز در هفته و ۵–۷ روز در هفته دسته‌بندی شد. برای ارزیابی ارتباطات، تحلیل‌های رگرسیون لجستیک و خطی چندمتغیره انجام شد و برای ارزیابی روابط دوز-پاسخ از تحلیل روند ترتیبی استفاده گردید. نسبت شانس تعدیل‌شده (AOR) و ضرایب رگرسیون (β) با فاصله اطمینان ۹۵٪ (CI) گزارش شد. سطح معناداری آماری در p < 0.05 تعیین شد. افزایش فراوانی مصرف قات به طور مستقل با افزایش شانس مدت خواب کوتاه‌تر (< ۶ ساعت) همراه بود. در مقایسه با افراد غیرمصرف‌کننده، شانس تعدیل‌شده مدت خواب کوتاه به طور پیشرونده افزایش یافت و در میان مصرف‌کنندگان روزانه به AOR برابر با 7.83 (95% CI: 3.70–16.57؛ P < 0.001) رسید. همچنین یک رابطه خطی دوز-پاسخ معنادار مشاهده شد (AOR = 1.97، 95% CI: 1.54–2.52؛ P < 0.001). نمرات اثرات ادراک‌شده با افزایش فراوانی مصرف قات به طور پیشرونده افزایش یافت، به طوری که تفاوت میانگین تعدیل‌شده برای گروه‌های ۱–۲، ۳–۴ و ۵–۷ روز در هفته به ترتیب 3.36، 3.73 و 4.94 بود (همه P ≤ 0.001) و روند خطی معناداری مشاهده شد (β تعدیل‌شده = 1.61، 95% CI: 1.29–1.92؛ P < 0.001). در مقابل، عملکرد تحصیلی هیچ ارتباط معنادار یا رابطه خطی دوز-پاسخ با مصرف قات نشان نداد (β تعدیل‌شده = 0.22، 95% CI: −0.46–0.89؛ P = 0.532). فراوانی مصرف قات ارتباطات دوز-پاسخ آشکاری با مدت خواب کوتاه و اثرات ادراک‌شده در میان دانشجویان پزشکی نشان داد. با این حال، این ارتباطات به تفاوت‌های قابل اندازه‌گیری در عملکرد تحصیلی منجر نشد. این یافته‌ها نشان می‌دهد که اثرات مصرف مکرر قات بیشتر در خواب و پیامدهای رفتاری ادراک‌شده مشهود است تا در موفقیت تحصیلی. این نتایج با اثرات شناخته‌شده محرک‌ها سازگار است و ممکن است به جمعیت‌های دانشجویی مشابه در شرایط قابل مقایسه نیز تعمیم یابد.

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موضوع‌ها و کلیدواژه‌ها

ادراکدانشجویانشناختacademic performancechewing frequencydose-response relationshipkhat chewingmedical studentsperceived consequencesshort sleep durationsleep duration

ارجاع

Obadi, A. A., Al‐Adhroey, A. H., Amad, M. A. A., Salman, H. A., Alsaedi, A. M., Al-Yamani, A. A., Mahyoob, E. M., Al-Pai, M. S., & Dughaish, A. A. (2026). Dose–response relationship between khat chewing frequency and sleep duration, perceived effects, and academic performance among medical students in Yemen. Scientific Reports. https://doi.org/10.1038/s41598-026-72988-9

(Obadi et al., 2026)

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  1. با احترام و بدون توهین، تحقیر، برچسب‌زنی یا حمله‌ی شخصی با دیگران گفتگو کنید.
  2. از نوشتن هرگونه اطلاعات هویتی یا قابل‌شناسایی مراجعان، بیماران یا اشخاص ثالث، از جمله نام، شماره‌ی تماس، تصویر، نشانی، محل کار یا جزئیات منحصربه‌فرد پرونده خودداری کنید.
  3. اگر درباره‌ی یک تجربه‌ی بالینی سؤال می‌کنید، اطلاعات را تا حد ممکن بی‌نام و کلی بیان کنید تا امکان شناسایی فرد وجود نداشته باشد.
  4. این بخش برای یادگیری و گفت‌وگوی علمی است و جایگزین ارزیابی، تشخیص، مشاوره یا روان‌درمانی شخصی نیست.
  5. در شرایط بحران یا خطر آسیب به خود یا دیگران، به این بخش اتکا نکنید و برای دریافت کمک فوری با اورژانس اجتماعی ۱۲۳ یا صدای مشاور بهزیستی ۱۴۸۰ تماس بگیرید.
  6. انتشار تبلیغات، معرفی خدمات شخصی، شماره‌ی تلفن، شناسه‌ی شبکه‌های اجتماعی، پیوند تبلیغاتی یا درخواست جذب مراجع در این بخش مجاز نیست.
  7. در بیان ادعاهای علمی، به‌ویژه درباره‌ی اثربخشی درمان‌ها، تشخیص یا یافته‌های پژوهشی، تا حد امکان نام منبع معتبر، مقاله یا راهنمای علمی را ذکر کنید.
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  9. پاسخ‌هایی که کارشناسان فکر بنیان می‌دهند با برچسب «پاسخ فکر بنیان» یا «کارشناس فکر بنیان» نمایش داده می‌شوند و سایر نوشته‌ها بیانگر نظر کاربران هستند.
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چکیده

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